Derek Lowe writes about the "hot" field of activity-based protein profiling, which he explains via a critique of a current paper out of Benjamin Cravatt's lab at Scripps. His paper tested the most effective ways to photoaffinity-label histone deacetylase enzymes and found that in vitro and in vivo results are not always the same. Lowe emphasizes that in drug discovery especially, assumptions should never be made.

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NPR reports that with medical data being big business, some companies want to get patients involved.

The Asbury Park Press reports on the startup Genomic Prediction's test to determine an embryo's risk of disease.

In PNAS this week: optical mapping allows glimpse of structural variants, disease-linked GATA2 mutations boosts its protein activity, and more.

Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.