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The Downside of Pharmacogenomics: Sorry, You May Be a Nonresponder

Studies published in the Lancet and the New England Journal of Medicine this week provide the basis for this article in the Wall Street Journal, which reports that "patients with a particular gene variant seem to respond less effectively to the anticlotting agent Plavix than those with the normal version of the gene." Researchers wonder whether higher doses of Plavix would make a difference for people with the variant, or whether the drug will simply be ineffective for them, noting that more studies are needed.


The Scan

Rise of BA.5

The New York Times reports that the Omicron subvariant BA.5 has become the dominant version of SARS-CoV-2 in the US.

UK Health Secretary Resigns

Sajid Javid, the UK health secretary, resigned along with Chancellor Rishi Sunak, saying they cannot work with Prime Minister Boris Johnson's government, CNN reports.

Clones From Freeze-Dried Cells

A team in Japan has cloned mice from freeze-dried skin cells, according to the Guardian.

Genome Research Papers on Craniosynostosis, Macaque Retrotransposition, More

In Genome Research this week: structural variants in craniosynostosis, LINE-1 activity in rhesus macaque brain, and more.