Many people in the US are being over-diagnosed and over-treated for cancer and better definitions of cancer and new molecular diagnostic technologies could help solve the problem, according to a working group of the National Cancer Institute.

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In Nature this week: genomic analysis of high-grade serous ovarian cancer, and more.

The new Riken president outlines some of his plans for the institute.

The Guardian discusses whether big science projects are worth the loss of resources available for other scientific pursuits.

An NEJM update from the ClinVar team highlights the difficulties of interpreting genetic variants.