A commentary published in Nature this week argues that the National Institutes of Health is not meeting its mandate to fund "the best science, by the best scientists."

Indeed, based on an analysis of 1,380 papers published since 2001 that have received 1,000 citations or more — a "proxy" measurement for the influence of the work — the authors found that "three out of five authors of these influential papers do not currently have NIH funding as principal investigators."

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