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Divining the Future

There's a thread at SeqAnswers that asks whether researchers will stop using the Roche 454 as the Illumina chemistry improves. While the answers vary, many contributors to the thread note that Roche "won't stand still," as Maubp puts it.

Mike the Mad Biologist gives his take on his own blog, where he says that he has already stopped using 454 for his microbial genomics work. "Compared to Illumina assemblies that use 5 kb jumps (and are thus able to span most of the repetitive regions), 454 isn't even in the same league," Mike says. "Combined with the much lower cost of generating Illumina sequence data, 454 is really out of the bacterial genome game." However, Mike adds that "I could see 454 being useful if you need long reads and not that many of them."

The Scan

Vaccine Update Recommended

A US Food and Drug Administration panel recommends booster vaccines be updated to target Omicron, CNBC reports.

US to Make More Vaccines for Monkeypox Available

The US is to make nearly 300,000 vaccine doses available in the coming weeks to stem the spread of human monkeypox virus, according to NPR.

Sentence Appealed

The Associated Press reports that Swedish prosecutors are appealing the sentence given to a surgeon once lauded for transplanting synthetic tracheas but then convicted of causing bodily harm.

Genome Biology Papers on COVID-19 Effector Genes, Virtual ChIP-seq, scDART

In Genome Biology this week: proposed COVID-19 effector genes, method to predict transcription factor binding patterns, and more.