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Directions for Building a Supermodel

Genes for height and weight abound this week. In mice, weight is regulated in part by the adp regulatory gene, reported a team from the University of Texas Southwestern Medical Center. This gene is located in a region of the genome already associated with obesity and type 2 diabetes. Another group used a genome-wide search of more than 34,000 people to find that the HMGA2 gene affects height, though only a small percentage of variation is seen among people. The researchers, though, are still on the lookout for more height genes.

We at GTO are wondering when someone is going to use this knowledge to build an army of supermodels -- and whether RNAi can be used to turn us into supermodels, too.


The Scan

Rise of BA.5

The New York Times reports that the Omicron subvariant BA.5 has become the dominant version of SARS-CoV-2 in the US.

UK Health Secretary Resigns

Sajid Javid, the UK health secretary, resigned along with Chancellor Rishi Sunak, saying they cannot work with Prime Minister Boris Johnson's government, CNN reports.

Clones From Freeze-Dried Cells

A team in Japan has cloned mice from freeze-dried skin cells, according to the Guardian.

Genome Research Papers on Craniosynostosis, Macaque Retrotransposition, More

In Genome Research this week: structural variants in craniosynostosis, LINE-1 activity in rhesus macaque brain, and more.