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Digging the Article

PLoS recently launched its article-level metrics program for all of its journals. At O'Really, Duncan Hull takes a look at the data from the top 10 papers. He says that "this is novel, interesting and potentially useful data, not currently made publicly available by other publishers."

DrdrA at Blue Lab Coats is also intrigued. "I love this feature because it reflects reality to the level of readership of a given article better and more immediately than the traditional pre-electronic media age measures such as citation rate or total citation number could," she writes.

Hull also warns that "analysing this data is not straightforward" and that "popularity and importance are not the same thing."

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.