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A Different Kind of Celebrity Genomics

Glenn Close is the newest person to have her entire genome sequenced, announces Illumina. Close's genome was sequenced to an average depth of 30 fold with a Genome Analyzer, making her the first "named female" to have her genome sequenced. At Genetic Future, Daniel MacArthur says "that's of negligible interest scientifically, but there's no doubt this will dramatically increase the public profile of whole genome sequencing."

"There is bipolar disorder and schizophrenia in my family, illnesses that, like other medical conditions, are thought to have genetic underpinnings," Close says in a statement. "As human sequencing becomes increasingly routine, my hope is that researchers will unravel the genetic aspects of mental illnesses to bring greater awareness about the diseases, de-stigmatize them and pave the way for more effective treatments."

Illumina adds that it plans to "create a social community for the education and exchange of information among those who have had their genomes sequenced."

The Scan

Fertility Fraud Found

Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today.

Ties Between Vigorous Exercise, ALS in Genetically At-Risk People

Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports.

Test Warning

The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK.

Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine

In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.