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Destroys and Creates

A number of technologies "are destroying markets and creating new ones," writes Technology Review. On its list of five such disruptive technologies is DNA sequencing. "Yet as fast-and-dirty DNA reading has improved, the industry is being swept by changes. One of the most remarkable: many researchers don't even buy sequencing machines any longer," Tech Review says. "Instead, when they need DNA decoded, they ship it out to mail-order laboratories that return results in a few days."

Other technologies on the list are e-readers, IBM's Watson computer, digital closed-circuit television, and 3-D printing.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.