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Deconstructing a Tumor

MIT's Technology Review reports that James Hicks and his colleagues at Cold Spring Harbor Laboratory have shown for the first time that it's possible to examine individual cells in a tumor to show the variability in its makeup. Until now, Technology Review's Lauren Gravitz reports, most tumor analysis has been done on thousands of cells at once, "a method that can obscure individual variation and can cause researchers to misidentify a cancer's aggressiveness." But Hicks' technique allows researchers to sort through and separate the cells, and amplify parts of their genome. "Once you know the different populations of cancer cells, you can use therapies that target all of them and eradicate much more of the disease," Gravitz says.

The Scan

Two J&J Doses

Johnson & Johnson says two doses of its SARS-CoV-2 vaccine provides increased protection against symptomatic COVID-19, CNN reports.

Pfizer-BioNTech Vaccine Response in Kids

The Pfizer-BioNTech SARS-CoV-2 vaccine in a lower-dose format appears to generate an immune response among children, according to the Washington Post.

Chicken Changes to Prevent Disease

The Guardian writes that researchers are looking at gene editing chickens to help prevent future pandemics.

PNAS Papers on Siberian Dog Ancestry, Insect Reproduction, Hippocampal Neurogenesis

In PNAS this week: ancestry and admixture among Siberian dogs, hormone role in fruit fly reproduction, and more.