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Abel Pharmboy woke up depressed; today is the 19th anniversary of his dissertation defense, and wonders how he ever got through it. His perception of his performance that day ("I was a blithering idiot during my oral exam.") is much different from others' ("Several of my friends, and those who were not exactly friends, said it was the best talk I ever gave.").

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The World Health Organization will be providing low-cost COVID-19 tests to low- and middle-income nations, according to Reuters.

Nature News examines how the confirmation of Amy Coney Barrett to the US Supreme Court could affect scientific agencies.

Nobel Prize-winner Arthur Ashkin, who developed optical tweezers, has died at 98, the Washington Post reports.

In PNAS this week: altered gene expression in brain samples from Alzheimer's disease patients, effects of gene mutations found in bladder cancer, and more.