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CRISPR Possibilities

Because of its ability to edit genomes, CRISPR technology is catching the attention of a number of scientists, NPR reports.

"It's really powerful, it's a really exciting development," the University of Massachusetts Medical School's Craig Mello tells NPR's All Things Considered.

Though Mello won the Nobel Prize for his work on RNA interference, he says that CRISPR may be more useful "because now you can essentially change a genome at will to almost anything you want."

Indeed, he's started a company called CRISPR Therapeutics to develop the tool for the clinic. He's focusing in particular on genetic blood disorders like sickle cell anemia and thalassemia.

"Though a lot of testing still needs to be done before doctors can say the CRISPR technique is safe and effective enough for use in treating patients, even many scientists not directly involved in the research are enthusiastic about its possibilities," NPR's Joe Palca says.

The Scan

Foxtail Millet Pangenome, Graph-Based Reference Genome

Researchers in Nature Genetics described their generation of a foxtail millet pangenome, which they say can help in crop trait improvement.

Protein Length Distribution Consistent Across Species

An analysis in Genome Biology compares the lengths of proteins across more than 2,300 species, finding similar length distributions.

Novel Genetic Loci Linked to Insulin Resistance in New Study

A team reports in Nature Genetics that it used glucose challenge test data to home in on candidate genes involved in GLUT4 expression or trafficking.

RNA Editing in Octopuses Seems to Help Acclimation to Shifts in Water Temperature

A paper in Cell reports that octopuses use RNA editing to help them adjust to different water temperatures.