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Core Concept

Core lab scientists allow for efficient and cost-effective research, but their efforts can go unacknowledged by the public, writes Richard Wintle from the Hospital for Sick Children in Toronto at Occam's Corner in The Guardian. "When [core lab research is] done right, it may also be completely invisible to the public, who may never know that money from their taxes is buying much more efficient research than would otherwise be possible," he says. While the US National Institutes of Health spends about $900 million a year on core facilities, Wintle notes that those funds can help a vast number of scientists. His genomics core lab, which has received $5.1 million from Genome Canada to support two years of operations, each year receives work from about 800 other labs around the world, leading to more than 100 studies a year that acknowledge his lab's contribution. "Just imagine the impact the larger investments by the NIH, MRC, and other agencies have in enabling scientists to do research," he adds.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.