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Confirmed

Earlier this week, bloggers discussed the rumored closure of the National Center for Biotechnology Information's Short Read Archive repository. NCBI has confirmed that it will discontinue the SRA, as well as its Trace Archive and Peptidome repositories. "Over the next few weeks, we will phase out the [Peptidome] online browser, query, and display interface," NCBI says, though it adds that "all existing data and metadata files will continue to be made available from our ftp server indefinitely." As for the SRA and Trace Archive databases, NCBI says that "closure … will occur in phases." In the coming weeks, SRA and Trace will stop accepting certain submissions, and within the next 12 months, it will no longer accept any submissions. During that time, "NCBI will be working with staff from NIH Institutes that fund large-scale sequencing efforts to develop an approach for future access to and storage of the existing data," the agency says, adding that it intends to continue its support for the development of "information resources for biological data derived from next-generation sequencing." NCBI suggests that investigators deposit their sequence assemblies and gene expression data to a variety of repositories, including the Gene Expression Ombnibus; dbVar, dbGap, and dbSNP; and GenBank, among others.

At our sister publication BioInform, Uduak Grace Thomas has more from NCBI's David Lipman.

The Scan

Renewed Gain-of-Function Worries

The New York Times writes that the pandemic is renewing concerns about gain-of-function research.

Who's Getting the Patents?

A trio of researchers has analyzed gender trends in biomedical patents issued between 1976 and 2010 in the US, New Scientist reports.

Other Uses

CBS Sunday Morning looks at how mRNA vaccine technology could be applied beyond SARS-CoV-2.

PLOS Papers Present Analysis of Cervicovaginal Microbiome, Glycosylation in Model Archaea, More

In PLOS this week: functional potential of the cervicovaginal microbiome, glycosylation patterns in model archaea, and more.