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"Complexity Is Winning"

At Ars Technica Robert Fortner writes that "synthetic biology does away with systems biology's untidiness by focusing on individual parts" but as it goes about that, it "rediscovers the complexity it hoped to escape." Fortner then looks into the work coming out of the Institute for Systems Biology and Lee Hood's protégés, as well as from other groups and companies. But they all seem to be coming up against the problem of complexity. "Although synthetic biology begins at the bottom and looks up, it eventually comes face to face with the same complexity that systems biology sees peering from the top down," Fortner writes. "In either direction, the more we look, the more we find. In the pincer movement of systems and synthetic biology on complexity, complexity is winning."

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.