If you thought math was something you could safely leave to those with calculator watches, think again. Mike the Mad Biologist has a post about why it's so important for biologists to be fluent in mathematics. He recounts a presentation he made to the Human Microbiome Project and the pushback he received on estimates of how much sequencing would be required for various projects. "Over and over, I was told that these estimates were 'counter-intuitive.' Why?