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A Coherent Call

In a New York Times op-ed James Watson makes a plea for restarting the "War on Cancer" — he says that "any claim that we are still 'at war' elicits painful sarcasm." He goes on to note that new vigor for the initiative should come from the top, as the US president is the one to pick the NCI head. Watson hopes that person provides strong leadership as well as experience in developing new pharmaceuticals. "I expect that my views will provoke rebuttals from prominent scientists who feel that it's not yet the time to go all out against cancer, and that until victory is more certain we should not further tap our limited coffers for more big-cancer money," Watson writes in conclusion. "While they are right that victory will not come from money alone, neither will it come from biding our time."

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.