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CNVs and ADHD

Cardiff University researchers and their colleagues found that people with attention-deficit hyperactivity disorder have an increased load of copy number variants. In The Lancet, they describe their genome-wide analysis 410 children with ADHD and 1,156 unrelated matched controls from Britain, an analysis that they repeated with Icelandic patients and controls. They point out that people with ADHD had "an excess of chromosome 16p13.11 duplications" and say that their findings indicate that "ADHD is not purely a social construct." Senior author Anita Thapar tells the Associated Press that "this is the first time we've found that children with ADHD have chunks of DNA that are either duplicated or missing."

The Scan

mRNA-Based Vaccine on the Way in China

China may soon have its own mRNA-based vaccine, according to Nature News.

Arranged Killing, Fraud Alleged by Prosecutors

The Wall Street Journal reports that prosecutors allege that the co-founder of a biotech arranged to have a business associate who threatened to expose him as a fraud killed.

Whirlwind Decade of CRISPR

The New York Times looks back at the 10 years since the University of California, Berkeley's Jennifer Doudna and her colleagues published their CRISPR paper.

PNAS Papers on Blue Cone Monochromacy Structural Variants, HIV-1 Mutant, T-ALL

In PNAS this week: structural variants linked to blue cone monochromacy, HIV-1 variants affecting the matrix protein p17, and more.