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Researchers at the Institute for Systems Biology used a computational approach to infer a transcriptional regulatory network in macrophage activation, identifying a possible new regulator in TGIF1. Their work was published recently in PLoS Computational Biology. They used sequencing, gene expression microarrays, and transcription factor binding site motif scanning to infer associations, and then followed up their predictions with ChIP-chip studies.

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NPR reports that researchers have developed chimeric embryos as part of work toward growing human organs in animals for organ transplants.

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