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Check It Before You Wreck It

"Contamination of various sorts has plagued genome projects from the get-go," complains Keith Robison at Omics! Omics!. Doing some background searching, he found a lot of contamination in sequence data sets, including plasmids and vectors among eukaryotic sequences. He says a New Year's resolution for everyone should be to recheck sequencing pipelines. "The solution is to run filters -- search everything you do against vectors, E.coli and other common contaminants. In addition, especially in this day-and-age, if your 'human' mRNA sequence doesn't match the genome, you've got some 'splaining to do," he writes.

The Scan

Gone, But Now Reconstructed SARS-CoV-2 Genomes

In a preprint, a researcher describes his recovery of viral sequences that had been removed from a common database.

Rare Heart Inflammation Warning

The Food and Drug Administration is adding a warning about links between a rare inflammatory heart condition and two SARS-CoV-2 vaccines, Reuters reports.

Sandwich Sampling

The New York Times sent tuna sandwiches for PCR analysis.

Nature Papers Describe Gut Viruses, New Format for Storing Quantitative Genomic Data, More

In Nature this week: catalog of DNA viruses of the human gut microbiome, new dense depth data dump format to store quantitative genomic data, and more.