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Check It Before You Wreck It

"Contamination of various sorts has plagued genome projects from the get-go," complains Keith Robison at Omics! Omics!. Doing some background searching, he found a lot of contamination in sequence data sets, including plasmids and vectors among eukaryotic sequences. He says a New Year's resolution for everyone should be to recheck sequencing pipelines. "The solution is to run filters -- search everything you do against vectors, E.coli and other common contaminants. In addition, especially in this day-and-age, if your 'human' mRNA sequence doesn't match the genome, you've got some 'splaining to do," he writes.

The Scan

Rise of BA.5

The New York Times reports that the Omicron subvariant BA.5 has become the dominant version of SARS-CoV-2 in the US.

UK Health Secretary Resigns

Sajid Javid, the UK health secretary, resigned along with Chancellor Rishi Sunak, saying they cannot work with Prime Minister Boris Johnson's government, CNN reports.

Clones From Freeze-Dried Cells

A team in Japan has cloned mice from freeze-dried skin cells, according to the Guardian.

Genome Research Papers on Craniosynostosis, Macaque Retrotransposition, More

In Genome Research this week: structural variants in craniosynostosis, LINE-1 activity in rhesus macaque brain, and more.