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Changing the Definition of Extinct

MD Anderson scientists have put the DNA of the extinct Tasmanian tiger back into transgenic mice to see how it would function, according to a paper published in PLoS ONE. Finding that thylacine Col2A1 enhancer directed chondrocyte-specific expression in the tiger the same way it does in mice, this is the first time that DNA from an extinct species has been used to examine function in a living organism. "Up until now we have only been able to examine gene sequences from extinct animals. This research was developed to go one step further to examine extinct gene function in a whole organism," says Andrew Pask, one of the study's authors, in this BBC article.

The Scan

Fertility Fraud Found

Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today.

Ties Between Vigorous Exercise, ALS in Genetically At-Risk People

Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports.

Test Warning

The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK.

Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine

In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.