Skip to main content
Premium Trial:

Request an Annual Quote

Challenge Accepted

Children's Hospital Boston has launched a competition to spur the use of genomic information in clinical care, reports The Wall Street Journal's Health Blog. Researchers participating in the $25,000-prize competition, called the CLARITY Challenge, will receive de-identified genomic data and medical histories for three patients with pediatric diseases and from their families, and will have to identify the best way to analyze the data, find relevant mutations, and report that information back to clinicians. A panel of judges, including Stanford's Russ Altman and Duke's Hunt Willard, will name the winner, the challenge's website adds. "[Genomic analysis] has come into practical fruition in the last couple of years, but a lot of work needs to be done to make it usable in a clinically responsible fashion," Children's Hospital Boston's Isaac Kohane tells the Health Blog. Findings from the competition will also be reported back to the families, it adds. The application deadline for researchers to participate in this challenge is March 1.

Our sister publication Clinical Sequencing News has more on CLARITY.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.