Certain Circumstances

The US Preventive Services Task Force has updated its recommendations for assessing and testing BRCA1 and BRCA2 mutations for breast and ovarian cancer susceptibility. As the task force's chair, Virginia Moyer, writes in the Annals of Internal Medicine, routine genetic screening in the absence of family history of the disease is not warranted.

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A genome-wide association study highlights a potential role for hair follicles in acne risk, according to New Scientist.

Newsday reports that breast cancer genetic testing guidelines for are out of date and may miss individuals.

In Cell this week: gene editing-based strategy to screen for immune system regulators, ancient plague patterns, and more.

Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.