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Cell Watchers

The Broad Institute has received a $32.5 million grant from the Klarman Family Foundation to open the Klarman Cell Observatory, a project focused on "deciphering how human cells are wired," an institute press release says. The Broad's Eric Lander says the project will create "a complete catalog of cell circuitry." This could help researchers understand how cells make "biological decisions" in their healthy and diseased states, the Broad adds, and may also help in the creation of new treatments and therapies. The Observatory "will foster groundbreaking discoveries and technological advances in cell circuit research. It will continue to propel advances in the experimental and computational methods needed to understand cell circuitry, and establish their broad applicability by studying a variety of cell type," the Broad says. Since much of what is known about cell circuitry comes from simple organisms like yeast and bacteria, the Observatory will focus on the cells of more complex organisms like humans and other mammals. The project will be led by Aviv Regev, the press release adds.

The Scan

Gone, But Now Reconstructed SARS-CoV-2 Genomes

In a preprint, a researcher describes his recovery of viral sequences that had been removed from a common database.

Rare Heart Inflammation Warning

The Food and Drug Administration is adding a warning about links between a rare inflammatory heart condition and two SARS-CoV-2 vaccines, Reuters reports.

Sandwich Sampling

The New York Times sent tuna sandwiches for PCR analysis.

Nature Papers Describe Gut Viruses, New Format for Storing Quantitative Genomic Data, More

In Nature this week: catalog of DNA viruses of the human gut microbiome, new dense depth data dump format to store quantitative genomic data, and more.