Even as US House Republicans propose some "tough numbers" for federally-funded research, they are also offering researchers "some grounds for optimism," says The Chronicle of Higher Education's Paul Basken. The House Appropriations Committee's recommendation for spending cuts in 2011 includes a suggested cut of $1.1 billion for the Department of Energy's Office of Science, and a $1 billion cut for NIH.

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NPR reports that with medical data being big business, some companies want to get patients involved.

The Asbury Park Press reports on the startup Genomic Prediction's test to determine an embryo's risk of disease.

In PNAS this week: optical mapping allows glimpse of structural variants, disease-linked GATA2 mutations boosts its protein activity, and more.

Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.