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Weighing the Options

Dr. Girlfriend at Life Beyond the Bench says that despite the frustrations she has experienced throughout her training in molecular biology, "deep down, I still want to be a professor." After all, she enjoys designing experiments and proposing projects — "the best part of my PhD was writing the thesis," she says. But Dr. Girlfriend has "always wished science had a fast forward button for all that tedious, and too often fruitless bench work." At the same time, Dr. Girlfriend acknowledges that being an academic PI can be tough; she's not sure whether the personal sacrifices she and her partner would have to make so that she could remain competitive in science would be worthwhile. Perhaps, in the end, "I think I would be happy doing bench work [at] a reasonably paid job rather than a desperate struggle to publish or perish," she says.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.