NIH managers aren't following the advice of review panels and are "giving hundreds of millions of dollars a year to scientists," namely young investigators, "whose projects are deemed less scientifically worthy than those denied money," says the New York Times. From a Government Accountability Office report, the Times says that 19 percent of awarded grants made in 2007 were exceptions, and is nearly double the 2003 level.

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The New York Times and ProPublica say that many physicians fail to disclose their financial ties when publishing in medical journals.

The Wall Street Journal reports Human Longevity's valuation has dropped by 80 percent.

Science reports that the US National Cancer Institute is cutting its operating budget by 5 percent.

In PLOS this week: similar variants seen in bullbogs, people with Robinow syndrome; ApoE genotypes in African-American, Puerto Rican populations; and more.