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Planning a Move? Try Tokyo, Boston, or Singapore City

Which world city is home to the most quality scientific research? According to statistics Nature has compiled, it depends — to some extent — on how scientific impact is quantified. As part of a news feature, Nature outlines the top cities for scientific research according to journal, publication, and citation metrics. In 2009, researchers in Boston published the most papers in Science, Nature, and PNAS (314, 247, and 857, respectively). Investigators in New York authored the second-most papers in Nature and PNAS in 2009 (166 and 454), while scientists in San Francisco authored 133 Science papers that year. Between 2006 and 2008, Tokyo took the top spot for total publications — its researchers pumped out 92,063 articles. Scientists in London produced 90,626 publications in that same period. Citation calculations from 2000 to 2008 show that Singapore City has seen a surge in citation impact. Nature dubs Austin a "rising star," as its researchers seem to "favor quality over quantity." On the flip-side, Beijing's "surging research output hasn't been matched by quality," according to Nature.

The Scan

Study Finds Sorghum Genetic Loci Influencing Composition, Function of Human Gut Microbes

Focusing on microbes found in the human gut microbiome, researchers in Nature Communications identified 10 sorghum loci that appear to influence the microbial taxa or microbial metabolite features.

Treatment Costs May Not Coincide With R&D Investment, Study Suggests

Researchers in JAMA Network Open did not find an association between ultimate treatment costs and investments in a drug when they analyzed available data on 60 approved drugs.

Sleep-Related Variants Show Low Penetrance in Large Population Analysis

A limited number of variants had documented sleep effects in an investigation in PLOS Genetics of 10 genes with reported sleep ties in nearly 192,000 participants in four population studies.

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.