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In a perspective piece appearing in this month's Molecular Biology of the Cell, the National Institute of General Medical Sciences' Marion Zatz discusses the rewards and challenges of her 27-year career as a program officer. "In the face of record deficits and shrinking National Institutes of Health budgets, one might wonder why a sane person would choose a career in government service," Zatz says.

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A small, early-stage trial of a combination therapy for brain cancer reports favorable responses in two patients, according to the Guardian.

Nature News writes that viral genomic surveillance in the US faces systemic issues.

President Joe Biden is seeking an increase in federal spending, including higher budgets for the National Institutes of Health and Centers for Disease Control and Prevention.

In PLOS this week: sex-stratified genome-wide association study of chronic pain, sequencing data from Indigenous Mexican groups, and more.