In discussing two studies on STEM career-related issues, Science Careers' Jim Austin says it's likely that many young investigators leave the STEM fields for lack of opportunities there. "Career-changers are often advised to avoid negativity. Admitting that you can't find a job is a bad idea for job seekers; few would answer that way even on a confidential survey," Austin says, referring to the sources of data for both studies.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.