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Nature News' Zoë Corbyn says that "as funding environments toughen, submitting more proposals is the best way to win grants." In a recent PLoS One analysis, the University of Wisconsin at Milwaukee's Paul Roebber and David Schultz at the University of Manchester and the University of Helsinki assessed the conditions under which submitting as many proposals as possible would be an efficient strategy. Corbyn says they found that when funding success rates fall below 15 percent, it's probably best to flood the proposal market. She adds that Roebber and Schultz drew upon game theory to determine "whether to approach scarcity in funding by working collectively to submit fewer proposals or working individually to submit more." Roebber tells Nature that as success rates dip, "inefficiencies in the system take over," and added that "the only way to counteract them is by putting in more and more proposals."

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.