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Initiating Independence

Several young investigators in Australia and the US this week received grants to get their independent research programs up and running.

The Australian Research Council named 277 researchers with recent PhDs who are to receive its inaugural Discovery Early Career Researcher Awards. According to The Australian, "the ARC diverted the $104 million funding handed out in DECRAs from its mainstream Discovery Grants program."

ARC's Margaret Sheil spoke with The Australian about the importance of supporting early-career researchers. "Once you have that independence it gives you credibility, negotiating power, and kudos that help you to do other things," Sheil said. "And in terms of attracting global talent, the entry point for most new blood is early in the career, not late," she added.

Meanwhile, the US National Institutes of Health Director's Early Independence Awards program announced its 10 winners, as well. Funding for the NIH Director's awards is supplied by the agency's Common Fund.

Applications for 2012 NIH Director's Early Independence Awards are due January 30, 2012.

The Scan

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.

Rett Syndrome Mouse Model Study Points to RNA Editing Possibilities

Investigators targeted MECP2 in mutant mouse models of Rett syndrome, showing in PNAS that they could restore its expression and dial down symptoms.

Investigators Find Shared, Distinct Genetic Contributors to Childhood Hodgkin Lymphoma

An association study in JAMA Network Open uncovers risk variants within and beyond the human leukocyte antigen locus.

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.