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Grants: Designed to Break Your Spirit

The story of "K" in a PLoS Biology Perspective article this week illustrates how difficult the current funding system makes life for new PIs. "To expect a young scientist to recruit and train students and postdocs as well as producing and publishing new and original work within two years (in order to fuel the next grant application) is preposterous," writes Peter Lawrence. He suggests that grant applications become shorter so that scientists writing, and reviewing, them spend less time on the bureaucracy and more time on science.

Adaptive Complexity's Michael White weighs in to say that the grant system has its "own peculiar logic" that is "brutal" and "discouraging" as the three-year grant cycle quickly goes boom-and-bust. "Whatever we do, we need to start taking the long view. Good research, in many cases, simply does not operate on a cycle that corresponds to the 3-year lab business cycle," he writes.

Larry Moran at The Sandwalk bemoans that no one has done anything to fix this known problem. "If the system isn't working then let's fix it," he says.

There's a related discussion at ScienceInsider in which the blogger Eli Kintisch discusses this Perspective article and other early career issues with scientists Christina Smolke and Natalie Mahowald.

The Scan

Renewed Gain-of-Function Worries

The New York Times writes that the pandemic is renewing concerns about gain-of-function research.

Who's Getting the Patents?

A trio of researchers has analyzed gender trends in biomedical patents issued between 1976 and 2010 in the US, New Scientist reports.

Other Uses

CBS Sunday Morning looks at how mRNA vaccine technology could be applied beyond SARS-CoV-2.

PLOS Papers Present Analysis of Cervicovaginal Microbiome, Glycosylation in Model Archaea, More

In PLOS this week: functional potential of the cervicovaginal microbiome, glycosylation patterns in model archaea, and more.