Writing in Source Code for Biology and Medicine, a trio of bioinformaticians presents a satire on working in the field that outlines how not to succeed. "By scrupulously following these guidelines one can be sure to regress at a highly satisfactory rate," the authors write.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.