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'Grantwriter's Agony'

In a recent post, DrugMonkey writes that he thinks the “worst possible score to receive on your NIH grant application is either ‘Triage’ … [or] ‘Above published or assumed payline.’” He writes that in the case of triage, the fate of the application was determined by only three assigned reviewers. In the case of the second determination, the program is not granted funding, but instead, the score suggests that it “might” be picked up, according to the blogger.

The Scan

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.

Study Highlights Pitfall of Large Gene Panels in Clinical Genomic Analysis

An analysis in Genetics in Medicine finds that as gene panels get larger, there is an increased chance of uncovering benign candidate variants.

Single-Cell Atlas of Drosophila Embryogenesis

A new paper in Science presents a single-cell atlas of fruit fly embryonic development over time.

Phage Cocktail Holds Promise for IBD

Researchers uncovered a combination phage therapy that targets Klebsiella pneumonia strains among individuals experiencing inflammatory bowel disease flare ups, as they report in Cell.