The Cancer Genome Atlas team reports in Nature on its study of 178 lung squamous cell carcinomas in which it found that such tumors are marked by complex genomic changes like rearrangements and copy number alterations. The TCGA team also notes that it found recurrent mutations in most samples, including TP53 mutations, and a number of pathways that are affected by those mutations. Further, the team reports that, for most tumors, it could identify potential therapeutic targets.