Cancer Characterization | GenomeWeb

The Cancer Genome Atlas team reports in Nature on its study of 178 lung squamous cell carcinomas in which it found that such tumors are marked by complex genomic changes like rearrangements and copy number alterations. The TCGA team also notes that it found recurrent mutations in most samples, including TP53 mutations, and a number of pathways that are affected by those mutations. Further, the team reports that, for most tumors, it could identify potential therapeutic targets.

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In Nature this week: genome-wide transcriptome analysis of brain samples from people with autism spectrum disorder, flounder genome, and more.

Researchers used T-cell transfer therapy to target mutation KRAS, according to the New York Times.

The US Senate has passed the 21st Century Cures Act, which would provide a funding boost at NIH while overhauling FDA policies.

Bloomberg reports that President-elect Donald Trump is considering Jim O'Neill for Food and Drug Administration commissioner.