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Calm Acceptance

Finding out that you are predisposed to Alzheimer's disease doesn't appear to impart any short-term psychological risks, according to a study in the New England Journal of Medicine. The researchers randomly assigned 162 adults with a parent with Alzheimer's disease to receive the results of their own APOE test or not and measured the participants for anxiety, depression, and test-related distress six weeks, six months, and one year afterward. There were no significant differences between the groups, other than the APOE4 negative group reporting less test-related distress. "Some people might say, 'I'm thinking about this a lot,' but it didn't translate into long-term depression or anxiety," author Scott Roberts says, according to Scientific Blogging.

At Technology Review, lead author Robert Green adds, "Even though patients clearly understood there was nothing they could do to stave off the disease, they had nonmedical reasons to learn about it: to prepare their children, to think about the longevity of careers."

The Scan

Highly Similar

Researchers have uncovered bat viruses that are highly similar to SARS-CoV-2, according to Nature News.

Gain of Oversight

According to the Wall Street Journal, the Biden Administration is considering greater oversight of gain-of-function research.

Lasker for mRNA Vaccine Work

The Scientist reports that researchers whose work enabled the development of mRNA-based vaccines are among this year's Lasker Award winners

PLOS Papers on Causal Variant Mapping, Ancient Salmonella, ALK Fusion Test for NSCLC

In PLOS this week: MsCAVIAR approach to map causal variants, analysis of ancient Salmonella, and more.