As a reviewer for the NIH Director's New Innovator Award in 2007, Science editor-in-chief Bruce Alberts says that his pile of applications contained "bold, original ideas" and that "at least 4 of my 35 should have been funded." None were, he adds. Alberts says that this grant award and similar ones focused on innovation "make a big difference to those who receive them. But there are far too few to change the culture for scientists starting new labs," he writes.