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The Bioethics Draft Picks

The membership of the Presidential Commission for the Study of Bioethical Issues was announced this week, and Summer Johnson, a blogger at the American Journal of Bioethics' blog, says she is "boggled" by the commission's composition. While the membership is highly qualified, she writes, the real issue is that it's unclear how the commission will fulfill the diverse obligations of its charter as the list of members "lacks creativity in terms of what a bioethics commission could have done," specifically exploring "revolutionary" scientific research.

However, among disciplines included on the panel are genetics – represented by Raju Kucherlapati from the Harvard Medical School Department of Genetics – HIV/AIDS, and cancer.

The Scan

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.

Rett Syndrome Mouse Model Study Points to RNA Editing Possibilities

Investigators targeted MECP2 in mutant mouse models of Rett syndrome, showing in PNAS that they could restore its expression and dial down symptoms.

Investigators Find Shared, Distinct Genetic Contributors to Childhood Hodgkin Lymphoma

An association study in JAMA Network Open uncovers risk variants within and beyond the human leukocyte antigen locus.

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.