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Bleak, but Not All Bad

Nature News' Erika Check Hayden says that in tough research funding times, DNA sequencing machine vendors are taking a hit. "Institutions are holding off buying the devices, leaving manufacturers feeling the pinch," she says, adding that although the National Institutes of Health's 2011 budget "is only 1 percent lower than it was in 2010, pessimism about future government spending has led analysts to predict much bigger budget cuts in 2012 and 2013 — and that pessimism has also had an impact on sequencing companies' share prices."

Citing a survey conducted by our parent company, GenomeWeb, in conjunction with Mizuho Securities and Illumina's recent Q3 earnings announcement, Nature says the market outlook is generally bleak. Fifty-eight percent of 94 respondents to the GenomeWeb-Mizuho Securities survey indicated that "talk of austerity had caused them to delay lab purchases," Check Hayden summarizes. Our sister publication GenomeWeb Daily News has more on Illumina's recent earnings report and planned restructuring.

But it's not all bad, Check Hayden says. "In light of the dismal news, many sequencing companies are now eyeing new markets in biomedicine, where whole-genome sequencing is beginning to make inroads." Illumina is hopeful that the "imminent release of a lower-cost version of its MiSeq sequencing machine will boost sales," she adds.

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.