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Binding Sites, Moving Targets

University of Pennsylvania scientists have applied the Derived Allele Frequency distribution test of neutrality on a set of transcription factor binding sites to find that many human- and primate-specific sites are likely evolving under positive selection. They published their findings today in PLoS ONE, showing that genes whose TF binding sites contain "high frequency derived alleles are enriched for positive regulation of protein metabolism and developmental processes," they write.

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.