Over at Genetic Future, Daniel MacArthur writes about the promises and challenges of big genetics. This year, he writes, we'll see major data releases from several large-scale projects, including the 1,000 Genomes Project and the Cancer Genome Atlas, and disease genetics consortia such as the Wellcome Trust Case Control Consortium, GIANT, and dozens of other groups.

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A research duo estimates in PLOS One the number of papers that have used misidentified cell lines.

UK's National Institute for Health and Care Excellence approves GlaxoSmithKline's SCID gene therapy despite cost.

Science reports that Brazilian researchers are petitioning for the reversal of budget cuts.

In PLOS this week: gene flow patterns in common ash, guidelines for using morpholinos in zebrafish, and more.