Skip to main content
Premium Trial:

Request an Annual Quote

'Betting on New Technology'

Genomic Health has made profit by selling state-of-the-art molecular diagnostics, but now it's time for some new technology to keep the company's growth momentum and revenue stream going, says Xconomy's Luke Timmerman. The company is investing in new diagnostic tests that look for patterns in more genes than today's molecular diagnostics can, Timmerman says. Genomic Health's current diagnostic workhorse, the Oncotype DX test which is used to predict the chance a woman's breast cancer will relapse, has an RT-PCR platform. But PCR becomes really expensive the more genes the test analyzes, Timmerman says, and now the company is looking for a replacement. Genomic Health is now looking into sequencing machines, which are getting cheaper and faster every year, he adds. Genomic Health is also focusing on the bioinformatics side of the equation, "and is working on iPhone, iPad, and Android-based mobile apps to help various consumers of genomic data get meaningful answers from the samples of DNA they sent in," Timmerman says.

The Scan

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.

SpliceVault Portal Provides Look at RNA Splicing Changes Linked to Genetic Variants

The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource.

Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study

Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages.

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.