Imagine that you are a government advisor and Congress and the White House hands you a sequestration notice saying that you have to cut around 5 percent or so out of an agency’s science budget next year. Unlike this year, when there was little time to plan and a clean cut was made roughly across the board, you may have a bit of time and leeway to make targeted cuts.

What would you do?

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A research duo estimates in PLOS One the number of papers that have used misidentified cell lines.

UK's National Institute for Health and Care Excellence approves GlaxoSmithKline's SCID gene therapy despite cost.

Science reports that Brazilian researchers are petitioning for the reversal of budget cuts.

In PLOS this week: gene flow patterns in common ash, guidelines for using morpholinos in zebrafish, and more.