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A Better Understanding of Clubfoot

Researchers at the Washington University School of Medicine are closer to understanding the birth defect that unites Damon Wayans, Dudley Moore, Kristi Yamaguchi, Troy Aikman, and Lord Byron: clubfoot. The findings, based on a genome-wide analysis that will appear in next week's American Journal of Human Genetics, show that clubfoot is likely to be caused by mutations in the PITX1 gene, which is thought to be involved in early lower limb development. "Identifying the genes for clubfoot will allow for improved genetic counselling and may potentially lead to new and improved treatment and preventive strategies for this disorder," lead author Matthew Dobbs told CBC News. He hopes that the research will one day make painful physical therapy treatments a thing of the past.


The Scan

CDC Calls Delta "Variant of Concern"

CNN reports the US Centers for Disease Control and Prevention now considers the Delta variant of SARS-CoV-2 to be a "variant of concern."

From FDA to Venture Capital

Former FDA Commissioner Stephen Hahn is taking a position at a venture capital firm, leading some ethicists to raise eyebrows, according to the Washington Post.

Consent Questions

Nature News writes that there are questions whether informed consent was obtained for some submissions to a database of Y-chromosome profiles.

Cell Studies on Multimodal Single-Cell Analysis, Coronaviruses in Bats, Urban Microbiomes

In Cell this week: approach to analyze multimodal single-cell genomic data, analysis of bat coronaviruses, and more.