A new study in the American Journal of Human Genetics has performed the first whole-genome linkage scan for synesthesia, which is known to run in families and to affect women more than it does men. Researchers found four candidate regions on chromosomes 2q24, 5q33, 6p12, and 12p12, and revealed that the disease, in which sounds are perceived as colors, is not X-linked as was previously thought. "The genetics of this form of synesthesia -- and probably that of other forms -- is far more complex than previously thought," says Mo at Neurophilosophy. Also of note, he points out the region with the strongest linkage is located on chromosome 2, known to contain a gene associated with autism. "Like synesthesia, autism involves sensory and perceptual abnormalities, and autistics often report synesthesia-like symptoms," he adds.
A Better Look at Synesthesia
Feb 07, 2009