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Best Friend, Best Model

Veterinary and human medicine are merging due to the completion of both the dog and human genomes, writes Elaine Ostrander from the National Institutes of Health in a review article in the New England Journal of Medicine. Dogs, she adds, are good models in which to study diseases — especially cancer — because most breeds were developed fairly recently, they descend from just a few founders, and have been under pressure from breeders to the point that recessive diseases are common and many breed are susceptible to certain disorders. Further, "the dog genome is very similar to humans," Ostrander tells HealthDay. "It's closer to us than the genomes of mice, rats or fruit flies, which are often used in research. Dogs also live side-by-side in our environments with us; they drink the same water, they breathe the same air, they're exposed to the same pesticides and they often even eat some of the same food."

The Scan

WHO Seeks Booster Pause

According to CNN, the World Health Organization is calling for a moratorium on administering SARS-CoV-2 vaccine boosters until more of the world has received initial doses.

For Those Long Legs

With its genome sequence and subsequent RNAi analyses, researchers have examined the genes that give long legs to daddy longlegs, New Scientist says.

September Plans

The New York Times reports that the US Food and Drug Administration is aiming for early September for full approval of the Pfizer-BioNTech SARS-CoV-2 vaccine.

Nucleic Acids Research Papers on Targeting DNA Damage Response, TSMiner, VarSAn

In Nucleic Acids Research this week: genetic changes affecting DNA damage response inhibitor response, "time-series miner" approach, and more.