US President Barack Obama's science report card is in, and it would appear that the chief executive of the US is something less than a straight-A student.

The Scientist recently surveyed experts from both sides of the political spectrum to get their views on how the president has done in five areas — health, environment, energy, science education, and space — since taking office.

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Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.