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Bacterial Hopscotch

When researchers talk about personal genomics, they likely aren't talking about this: A team at Northwestern University analyzed the genome sequence of 14 gonorrhea samples and found a human fragment of DNA in three of the isolates, reports New Scientist's Jessica Hamzelou. In their study published in mBio, the researchers say the DNA jump happened via horizontal gene transfer, but add that they've never seen DNA from a mammalian genome jump to a bacterial genome. What role the human DNA plays in the bacterium is still unknown — it's missing key sequences and isn't producing any functional proteins — but the discovery could have implications for how the bacteria adapt to the host, the researchers tells Hamzelou.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.