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Baby Steps for Personalized Medicine

Wei Zhang and others report this week in PNAS that a simple two-gene test can distinguish between two similar gastrointestinal cancers, gastrointestinal stromal tumor (GIST) and leiomyosarcoma (LMS). Using whole genome microarrays and analysis, authors from the
MDAndersonCancerCenter
and the Institute for Systems Biology were able to tell the two apart with about 87 percent accuracy.

Not only is this good news for systems biology, but it’s also a score for personalized medicine, which needs successes like this to push its way out into the world.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.